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Thread: Dietary Habit Is Associated with Depression and Intelligence: An Observational and Ge

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    Post Dietary Habit Is Associated with Depression and Intelligence: An Observational and Ge

    Title:
    Dietary Habit Is Associated with Depression and Intelligence: An Observational and Genome-Wide Environmental Interaction Analysis in the UK Biobank Cohort
    Abstract:
    Dietary habits have considerable impact on brain development and mental health. Despite long-standing interest in the association of dietary habits with mental health, few population-based studies of dietary habits have assessed depression and fluid intelligence. Our aim is to investigate the association of dietary habits with depression and fluid intelligence. In total, 814 independent loci were utilized to calculate the individual polygenic risk score (PRS) for 143 dietary habit-related traits. The individual genotype data were obtained from the UK Biobank cohort. Regression analyses were then conducted to evaluate the association of dietary habits with depression and fluid intelligence, respectively. PLINK 2.0 was utilized to detect the single nucleotide polymorphism (SNP) dietary habit interaction effect on the risks of depression and fluid intelligence. We detected 22 common dietary habit-related traits shared by depression and fluid intelligence, such as red wine glasses per month, and overall alcohol intake. For interaction analysis, we detected that OLFM1 interacted with champagne/white wine in depression, while SYNPO2 interacted with coffee type in fluid intelligence. Our study results provide novel useful information for understanding how eating habits affect the fluid intelligence and depression.

    pdf: nutrients-13-01150.pdf
    link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8067152/

  2. The Following 5 Users Say Thank You to Sansui Yang For This Useful Post:

     AlluGobi (08-28-2021),  Archetype0ne (09-05-2021),  Lenny Nero (08-18-2021),  Max_H (09-01-2021),  okarinaofsteiner (09-06-2021)

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    My dietary habits are better than they were,but still far from perfect.Culture fair/non-verbal/spatial tests have always been a relative weakness.The scores for the two high range,send to, spatial tests I've done are 113 &130.I'm significantly better at pattern recognition than mental rotation. I've had bouts of depression, but nothing major for a good number of years.
    Please support Mental health research and world community grid

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  4. The Following User Says Thank You to firemonkey For This Useful Post:

     Sansui Yang (08-23-2021)

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    Quote Originally Posted by firemonkey View Post
    My dietary habits are better than they were,but still far from perfect.Culture fair/non-verbal/spatial tests have always been a relative weakness.The scores for the two high range,send to, spatial tests I've done are 113 &130.I'm significantly better at pattern recognition than mental rotation. I've had bouts of depression, but nothing major for a good number of years.
    Come on! Keep a good mood~

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    Amazing post I really like it

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