Page 1 of 5 123 ... LastLast
Results 1 to 10 of 45

Thread: Kurdís Sun Sensitivity/Melanin/Melanoma SNP Project

  1. #1
    Banned
    Posts
    5,171
    Sex

    Post Kurdís Sun Sensitivity/Melanin/Melanoma SNP Project

    Hello everyone,

    Various SNPs have been implicated by various studies as having a correlation to sun sensitivity, melanin production, and melanoma risk.

    My goal is to group all the SNPs from the various studies into one spreadsheet, and either attempt to validate any correlation to the aforementioned, or perhaps at the very least attempt to determine whether there is an observable pattern. After inputting and organizing the data, my goal is to upload the spreadsheet, so that contributing members can draw their own conclusions. In addition to the spreadsheet, I will attempt to list the risk allele values for the SNPs.

    Meaningful conclusions can be formed if there is enough participants, with varying sun sensitivities, and skin tones.

    I will need the following information for the spreadsheet:

    1. The memberís ethnicity;
    2. The memberís eye color. Pick one of the following colors which is closest to your eye color:
    a. Blue
    b. Green
    c. Hazel
    d. Light Brown
    e. Dark Brown
    3. The memberís sun sensitivity. Please refer to the attached Fitzpatrick Sun Sensitivity chart to determine your sun sensitivity;Attachment 3154
    4. The memberís skin tone. Please confirm that your skin tone is comparable to one of the subjects on the Fitzpatrick chart;
    5. The memberís hair color. Please pick one of the following; Lt. blonde, dk blonde, red, light brown, medium brown, dark brown, and black;
    6. The memberís alleles for the following SNPs. I realize that most members, myself included, do not have results for all the SNPs listed:

    a. Rs1805005
    b. Rs1805006
    c. Rs1805008
    d. Rs2228479
    e. Rs4911414
    f. Rs12203592
    g. Rs1393350
    h. Rs26722
    i. Rs258322
    j. Rs4785763
    k. Rs12913832
    l. Rs966321
    m. Rs40132
    n. Rs12210050
    o. Rs17094273
    p. Rs352935
    q. Rs464349
    r. Rs11648785
    s. Rs1042602
    t. Rs16891982
    u. Rs3793976
    v. Rs2298458
    w. Rs3212363
    x. Rs819136
    y. Rs3212371
    z. Rs2311843


    I shall upload the spreadsheet after receiving data from 10 individuals, and shall update it with every additional 5 individuals thereafter.

    Thank you.

    My data is as follows:

    1- Kurd, N. Iraq;
    2- Green;
    3- Skin type IV;
    4- Skin tone IV;
    5- Dk. brown;
    6-
    a. Rs1805005 TG
    b. Rs1805006 CC
    c. Rs1805008 CC
    d. Rs2228479 GG
    e. Rs4911414 GG
    f. Rs12203592 CC
    g. Rs1393350 GG
    h. Rs26722 TC
    i. Rs258322 GG
    j. Rs4785763 CC
    k. Rs12913832 GG
    l. Rs966321
    m. Rs40132 AG
    n. Rs12210050
    p. Rs17094273
    q. Rs352935 TT
    r. Rs464349 TT
    s. Rs11648785 CC
    t. Rs1042602 AC
    u. Rs16891982
    v. Rs3793976
    w. Rs2298458 CC
    x. Rs3212363
    y. Rs819136 GG
    z. Rs3212371 AA
    bb. Rs2311843 TC

    Testing: Ancestry DNA
    Last edited by Kurd; 12-10-2014 at 02:48 AM.

  2. The Following User Says Thank You to Kurd For This Useful Post:

     ViktorL1 (12-17-2014)

  3. #2
    Gold Class Member
    Posts
    1,337
    Sex
    Location
    Sault Ste Marie, Ontario, Canada
    Ethnicity
    Irish Canadian
    Nationality
    Canada
    Y-DNA (P)
    L513->Z23516>BY11142
    mtDNA (M)
    H1bd

    Canada Ireland Scotland England Ireland County Tipperary Canada Old Newfoundland
    looks interesting, I will gather the info today if things dont get crazy around here and post it today, hopefully

    good luck with this
    Mike
    Furthest Y line=Patrick Whealen 1816-1874, b.Tipperary Co. Ire. d. Kincardine Ont.

    Y-DNA-RL21-L513-Z23516-BY11142('lost Irish 'C' boys?')

    FTDNA=P312+ P25+ M343+ M269+ M207+ M173+ L513+ U198- U152- U106- SRY2627- P66- P107- M73- M65- M37- M222- M18- M160- M153- M126- L705- L577- L193- L159.2- L1333-
    Big-Y=Z23516+
    23&me=L21+
    E.A.= S21-, S26-, S28-, S29-, S68-
    Geno 2 (N.G.P.) H1bd+

    Whalen/Phelan DNA Surname Project
    Hidden Content

  4. The Following User Says Thank You to MikeWhalen For This Useful Post:

     Kurd (12-09-2014)

  5. #3
    Gold Class Member
    Posts
    1,337
    Sex
    Location
    Sault Ste Marie, Ontario, Canada
    Ethnicity
    Irish Canadian
    Nationality
    Canada
    Y-DNA (P)
    L513->Z23516>BY11142
    mtDNA (M)
    H1bd

    Canada Ireland Scotland England Ireland County Tipperary Canada Old Newfoundland
    OK, here is my data:

    1-Canadian of Irish decent, 15/16 GGGrandparents from the British Isles-Irish/English/Scottish in that order-16th GGparent from Holland-stock
    2-Blue eyes
    3-FitzPatrick scale=Type 2
    4-skin tone is 'white skin' and matches the Type 2 on Fitzpatrick
    5-medium brown as adult, sandy blonde as kid, all white hair by age 35

    6-
    a. Rs1805005=GG
    b. Rs1805006=CC
    c. Rs1805008=CC
    d. Rs2228479=AG
    e. Rs4911414=GT
    f. Rs12203592=CC
    g. Rs1393350=GG
    h. Rs26722=CC
    i. Rs258322=AG
    j. Rs4785763=CC
    k. Rs12913832=GG
    l. Rs966321=GG
    m. Rs40132=AA
    n. Rs12210050=CC
    o. Rs1393350=GG
    p. Rs17094273=GG
    q. Rs352935=CC
    r. Rs464349=CC
    s. Rs11648785=CC
    t. Rs1042602=AA
    u. Rs16891982=GG
    v. Rs3793976=NIL
    w. Rs2298458=NIL
    x. Rs3212363=NIL
    y. Rs819136=GG
    z. Rs3212371=NIL
    aa. Rs2279727=NIL
    bb. Rs2311843=CC

    *My SNP results come from the 23&me v1 chip

    Good luck Kurd, it will be interesting to see how this works out

    Mike

    PS- of the 5 SNP's on your list that I did not have, I checked out my 'Big Y' raw data just in case one of them was to be found in the Y data, no luck, did not have them there either

    PPS-edited to conform with changed #4
    Last edited by MikeWhalen; 12-09-2014 at 03:05 PM.
    Furthest Y line=Patrick Whealen 1816-1874, b.Tipperary Co. Ire. d. Kincardine Ont.

    Y-DNA-RL21-L513-Z23516-BY11142('lost Irish 'C' boys?')

    FTDNA=P312+ P25+ M343+ M269+ M207+ M173+ L513+ U198- U152- U106- SRY2627- P66- P107- M73- M65- M37- M222- M18- M160- M153- M126- L705- L577- L193- L159.2- L1333-
    Big-Y=Z23516+
    23&me=L21+
    E.A.= S21-, S26-, S28-, S29-, S68-
    Geno 2 (N.G.P.) H1bd+

    Whalen/Phelan DNA Surname Project
    Hidden Content

  6. The Following 2 Users Say Thank You to MikeWhalen For This Useful Post:

     Kurd (12-09-2014),  Varun R (02-03-2015)

  7. #4
    Registered Users
    Posts
    294
    Sex
    Location
    Sweden
    Ethnicity
    Geat
    Nationality
    Swedish
    Y-DNA (P)
    G2a-S2808 FGC34809+
    mtDNA (M)
    I2

    Sweden European Union Kalmar Union
    Interesting! Hope you get a lot of takers. Here's my data:

    1. Swedish
    2. a (was unsure about this one, dunno where my greenish-grey eyes would fit best - but they were blue when I was little, so)
    3. Type III
    4. Matches Type II
    5. medium brown (paleish blond as a kid)
    6:
    a. Rs1805005 GG
    b. Rs1805006 CC
    c. Rs1805008 CC
    d. Rs2228479 GG
    e. Rs4911414 GG
    f. Rs12203592 CC
    g. Rs1393350 GG
    h. Rs26722 CC
    i. Rs258322 GG
    j. Rs4785763 CC
    k. Rs12913832 GG
    l. Rs966321 GT
    m. Rs40132 AA
    n. Rs12210050 CC
    o. Rs1393350 GG
    p. Rs17094273 GG
    q. Rs352935 CC
    r. Rs464349 CC
    s. Rs11648785 CC
    t. Rs1042602 AA
    u. Rs16891982 GG
    v. Rs3793976 CC
    w. Rs2298458 CC
    x. Rs3212363 AT
    y. Rs819136 GG
    z. Rs3212371 AA
    aa. Rs2279727 not found
    bb. Rs2311843 CC
    Last edited by Salkin; 12-10-2014 at 12:47 PM. Reason: Checked FTDNA data
    GEDmatch kits:
    M606752 (23andMe)
    F367588 (FTDNA)

    ySearch & mitoSearch: DK8FB

    FTDNA kit: 367588

  8. The Following 2 Users Say Thank You to Salkin For This Useful Post:

     Kurd (12-09-2014),  Varun R (02-03-2015)

  9. #5
    Banned
    Posts
    5,171
    Sex

    Quote Originally Posted by MikeWhalen View Post
    OK, here is my data:

    1-Canadian of Irish decent, 15/16 GGGrandparents from the British Isles-Irish/English/Scottish in that order-16th GGparent from Holland-stock
    2-Blue eyes
    3-FitzPatrick scale=Type 2
    4-skin tone is #3 or 'light'
    5-medium brown as adult, sandy blonde as kid, all white hair by age 35

    6-
    a. Rs1805005=GG
    b. Rs1805006=CC
    c. Rs1805008=CC
    d. Rs2228479=AG
    e. Rs4911414=GT
    f. Rs12203592=CC
    g. Rs1393350=GG
    h. Rs26722=CC
    i. Rs258322=AG
    j. Rs4785763=CC
    k. Rs12913832=GG
    l. Rs966321=GG
    m. Rs40132=AA
    n. Rs12210050=CC
    o. Rs1393350=GG
    p. Rs17094273=GG
    q. Rs352935=CC
    r. Rs464349=CC
    s. Rs11648785=CC
    t. Rs1042602=AA
    u. Rs16891982=GG
    v. Rs3793976=NIL
    w. Rs2298458=NIL
    x. Rs3212363=NIL
    y. Rs819136=GG
    z. Rs3212371=NIL
    aa. Rs2279727=NIL
    bb. Rs2311843=CC

    *My SNP results come from the 23&me v1 chip

    Good luck Kurd, it will be interesting to see how this works out

    Mike

    PS- of the 5 SNP's on your list that I did not have, I checked out my 'Big Y' raw data just in case one of them was to be found in the Y data, no luck, did not have them there either
    Mike,

    I updated the Fitzpatrick chart with one that I believe to be slightly more accurate, and also modified paragraph 4. Please confirm that the changes do not affect your results.

    Thanks

  10. #6
    Banned
    Posts
    5,171
    Sex

    Salkin,

    I updated the Fitzpatrick chart with one that I believe to be slightly more accurate, and also modified paragraph 4. Please confirm that the changes do not affect your results.

    Thanks

  11. #7
    Registered Users
    Posts
    529
    Sex
    Location
    England
    Ethnicity
    English
    Nationality
    British
    Y-DNA (P)
    I1a1b1
    mtDNA (M)
    H1c3

    England Ireland Wales Scotland England North of England European Union
    Here's mine -

    1. Mostly English, some Irish and Welsh, more distant Scottish and two of my great grandfathers are unknown.
    2. Blue eyes.
    3. Type III.
    4. Type II.
    5. My hair was black as a baby, lightened to dark brown which is the colour it is today.

    a. Rs1805005 GG
    b. Rs1805006 CC
    c. Rs1805008 CC
    d. Rs2228479 GG
    e. Rs4911414 GG
    f. Rs12203592 CT
    g. Rs1393350 AG
    h. Rs26722 CC
    i. Rs258322 GG
    j. Rs4785763 CC
    k. Rs12913832 GG
    l. Rs966321 GT
    m. Rs40132 AA
    n. Rs12210050 CC
    o. Rs1393350 AG
    p. Rs17094273 GG
    q. Rs352935 TT
    r. Rs464349 TT
    s. Rs11648785 CT
    t. Rs1042602 AC
    u. Rs16891982 GG
    v. Rs3793976 CC
    w. Rs2298458 CC
    x. Rs3212363 AA
    y. Rs819136 GG
    z. Rs3212371 AA
    aa. Rs2279727 not found
    bb. Rs2311843 CC

  12. The Following 2 Users Say Thank You to Stephen1986 For This Useful Post:

     Kurd (12-09-2014),  Varun R (02-03-2015)

  13. #8
    Registered Users
    Posts
    294
    Sex
    Location
    Sweden
    Ethnicity
    Geat
    Nationality
    Swedish
    Y-DNA (P)
    G2a-S2808 FGC34809+
    mtDNA (M)
    I2

    Sweden European Union Kalmar Union
    Quote Originally Posted by Kurd View Post
    Salkin,

    I updated the Fitzpatrick chart with one that I believe to be slightly more accurate, and also modified paragraph 4. Please confirm that the changes do not affect your results.

    Thanks
    Sun sensitivity just barely ended up Type III with that one (mainly due to my complete lack of freckles). I updated my post accordingly.
    GEDmatch kits:
    M606752 (23andMe)
    F367588 (FTDNA)

    ySearch & mitoSearch: DK8FB

    FTDNA kit: 367588

  14. The Following User Says Thank You to Salkin For This Useful Post:

     Kurd (12-09-2014)

  15. #9
    Banned
    Posts
    5,171
    Sex

    Quote Originally Posted by Stephen1986 View Post
    Here's mine -

    1. Mostly English, some Irish and Welsh, more distant Scottish and two of my great grandfathers are unknown.
    2. Blue eyes.
    3. Type III.
    4. Type II.
    5. My hair was black as a baby, lightened to dark brown which is the colour it is today.

    a. Rs1805005 GG
    b. Rs1805006 CC
    c. Rs1805008 CC
    d. Rs2228479 GG
    e. Rs4911414 GG
    f. Rs12203592 CT
    g. Rs1393350 AG
    h. Rs26722 CC
    i. Rs258322 GG
    j. Rs4785763 CC
    k. Rs12913832 GG
    l. Rs966321 GT
    m. Rs40132 AA
    n. Rs12210050 CC
    o. Rs1393350 AG
    p. Rs17094273 GG
    q. Rs352935 TT
    r. Rs464349 TT
    s. Rs11648785 CT
    t. Rs1042602 AC
    u. Rs16891982 GG
    v. Rs3793976 CC
    w. Rs2298458 CC
    x. Rs3212363 AA
    y. Rs819136 GG
    z. Rs3212371 AA
    aa. Rs2279727 not found
    bb. Rs2311843 CC
    Stephen,

    It looks like almost all of your SNPs have been tested, unlike many of us. What testing service did you use, or did you use multiple services?

  16. #10
    Registered Users
    Posts
    529
    Sex
    Location
    England
    Ethnicity
    English
    Nationality
    British
    Y-DNA (P)
    I1a1b1
    mtDNA (M)
    H1c3

    England Ireland Wales Scotland England North of England European Union
    Quote Originally Posted by Kurd View Post
    Stephen,

    It looks like almost all of your SNPs have been tested, unlike many of us. What testing service did you use, or did you use multiple services?
    My results are from 23andMe.

  17. The Following User Says Thank You to Stephen1986 For This Useful Post:

     Kurd (12-09-2014)

Page 1 of 5 123 ... LastLast

Similar Threads

  1. Replies: 81
    Last Post: 06-28-2021, 01:23 AM
  2. Replies: 25
    Last Post: 10-06-2020, 02:25 PM
  3. Replies: 61
    Last Post: 09-20-2017, 03:04 PM
  4. help for redheads & melanoma
    By MikeWhalen in forum Medical Genetics
    Replies: 2
    Last Post: 09-15-2017, 12:26 AM
  5. "Biological explanation for wheat sensitivity found"
    By Amerijoe in forum Health and Fitness
    Replies: 0
    Last Post: 07-26-2016, 06:54 PM

Tags for this Thread

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •