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Thread: Irish DNA Atlas, Preliminary Results

  1. #11
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    I contacted the event organiser and the (voice) pod cast probably will not be available until October, by which time we should already have an update at Genetic Genealogy Ireland.
    I also contacted Gianpiero to clarify a couple of points eg FGS or Genotype chip platform and R1b-M269 frequency which to me appears high.
    Gerard Corcoran
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    Well I imagine it depends on what version of R tree they used when designing that part of their SNP chip. Lets hope it isn't this one:



    Cause that's partying like it's 2005! Even 2009 would be major improvement on that!


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    Quote Originally Posted by Dubhthach View Post
    Any idea when a paper will be released etc? Also what size SNP chip were they using. Obviously with average age of 61 for participants and average time "great grandparent lived" at 1848, it gives a snapshot into generation that survived the Great Famine (1847 obviously remembered as infamous "Back 47")

    A similiar result for Connacht/Munster make sense given that both provinces remained as majority Irish speaking provinces until at least the Famine period, Leinster obviously had most admixture over the preceeding 800 years.
    My understanding is that because of the less strict criteria on POBI ie 4 g parents v 8 gg parents the average time g parents lived in POBI was late 19th century.
    I have written to Gianpiero asking for clarification on the sequencing platform used.
    There was no date for publication and I believe they want to recruit more participants especially in areas of no coverage. We will have a member of the IDA team present at GGI2015 in October.
    Last edited by Heber; 08-05-2015 at 06:03 PM.
    Gerard Corcoran
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    Quote Originally Posted by Heber View Post
    He showed this slide so I guess he is following a similar methodology.
    At this early stage he showed three main admixture components
    Atlantic (WE Seaboard)
    North Europe
    South Europe
    Atlantic was the dominant component in Ireland.
    It may be that subsequent detailed analysis will include higher granularity.
    Interesting that the Atlantic component is dominant in Ireland. The POBI project seem to have picked up a similar thing with their FRA14 (Atlantic?) component which is particularly strong in Wales.

    These results though do seem to be at odds with other sources where the Irish sit closer to North Sea areas. I am particularly thinking of Eurogenes K15 where Irish, Scottish and English all have higher North Sea components than Atlantic components.

    I can only think that the Irish DNA Atlas sampling and methodology is different to Eurogenes, etc.

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    Quote Originally Posted by avalon View Post
    Interesting that the Atlantic component is dominant in Ireland. The POBI project seem to have picked up a similar thing with their FRA14 (Atlantic?) component which is particularly strong in Wales.

    These results though do seem to be at odds with other sources where the Irish sit closer to North Sea areas. I am particularly thinking of Eurogenes K15 where Irish, Scottish and English all have higher North Sea components than Atlantic components.

    I can only think that the Irish DNA Atlas sampling and methodology is different to Eurogenes, etc.
    They used the same name for a different, higher K component.

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    Quote Originally Posted by Dubhthach View Post
    I would hope that the SNP chip would at least have a bit of wider SNP choice than just M269 and M222 when it comes to Y-Chromosome
    Update:
    "we have only genotyped (illumina omniXpress), we have not yet sequenced beyond the work published by Mark Jobling on Y."
    Gerard Corcoran
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    Quote Originally Posted by Generalissimo View Post
    They used the same name for a different, higher K component.
    Sorry, could you explain that in more detail? My knowledge of admixture calculators is quite limited.

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    Quote Originally Posted by avalon View Post
    Sorry, could you explain that in more detail? My knowledge of admixture calculators is quite limited.
    They're not using Admixture, but it's basically as if they went up to a K20 where there was a more specific Irish component. So what they're doing is similar to the 23andMe AC, and focusing on more recent ancestry, rather than subtle differences in the levels of more widely spread components to recognize Irish people.

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  17. #19
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    Quote Originally Posted by avalon View Post
    Interesting that the Atlantic component is dominant in Ireland. The POBI project seem to have picked up a similar thing with their FRA14 (Atlantic?) component which is particularly strong in Wales.

    These results though do seem to be at odds with other sources where the Irish sit closer to North Sea areas. I am particularly thinking of Eurogenes K15 where Irish, Scottish and English all have higher North Sea components than Atlantic components.

    I can only think that the Irish DNA Atlas sampling and methodology is different to Eurogenes, etc.
    Their Irish sample is large and their complete dataset most likely does not have the same populations used to make Eurogenes calculators. Both of these factors will make it easier for an Irish modal component to form.

    In the run below (from Paschou et al. 2014) you can see that some Irish individuals are already getting their own light green component at K=8.


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    That's not an Irish cluster. It looks like they didn't remove a few relatives IMO.

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