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Thread: New DNA Papers

  1. #1291
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    Kyrgyzstan
    https://www.nature.com/articles/s10038-020-0781-3

    Article
    Open Access
    Published: 01 June 2020

    Papuan mitochondrial genomes and the settlement of Sahul

    Nicole Pedro, Nicolas Brucato, Veronica Fernandes, Mathilde André, Lauri Saag, William Pomat, Céline Besse, Anne Boland, Jean-François Deleuze, Chris Clarkson, Herawati Sudoyo, Mait Metspalu, Mark Stoneking, Murray P. Cox, Matthew Leavesley, Luisa Pereira & François-Xavier Ricaut

    Journal of Human Genetics (2020)

    Abstract

    New Guineans represent one of the oldest locally continuous populations outside Africa, harboring among the greatest linguistic and genetic diversity on the planet. Archeological and genetic evidence suggest that their ancestors reached Sahul (present day New Guinea and Australia) by at least 55,000 years ago (kya). However, little is known about this early settlement phase or subsequent dispersal and population structuring over the subsequent period of time. Here we report 379 complete Papuan mitochondrial genomes from across Papua New Guinea, which allow us to reconstruct the phylogenetic and phylogeographic history of northern Sahul. Our results support the arrival of two groups of settlers in Sahul within the same broad time window (50–65 kya), each carrying a different set of maternal lineages and settling Northern and Southern Sahul separately. Strong geographic structure in northern Sahul remains visible today, indicating limited dispersal over time despite major climatic, cultural, and historical changes. However, following a period of isolation lasting nearly 20 ky after initial settlement, environmental changes postdating the Last Glacial Maximum stimulated diversification of mtDNA lineages and greater interactions within and beyond Northern Sahul, to Southern Sahul, Wallacea and beyond. Later, in the Holocene, populations from New Guinea, in contrast to those of Australia, participated in early interactions with incoming Asian populations from Island Southeast Asia and continuing into Oceania.

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  3. #1292
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    Puerto Rico Cuba
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    Last edited by Milkyway; 06-01-2020 at 09:15 PM.

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  5. #1293
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    Ancient admixture into Africa from the ancestors of non-Africans

    Ancient admixture into Africa from the ancestors of non-Africans
    Christopher Bernard Cole, Sha Joe Zhu, Iain Mathieson, Kay Prfüer, Gerton Lunter

    Abstract
    Genetic diversity across human populations has been shaped by demographic history, making it possible to infer past demographic events from extant genomes. However, demographic inference in the ancient past is difficult, particularly around the out-of-Africa event in the Late Middle Paleolithic, a period of profound importance to our species' history. Here we present SMCSMC, a Bayesian method for inference of time-varying population sizes and directional migration rates under the coalescent-with-recombination model, to study ancient demographic events. We find evidence for substantial migration from the ancestors of present-day Eurasians into African groups between 40 and 70 thousand years ago, predating the divergence of Eastern and Western Eurasian lineages. This event accounts for previously unexplained genetic diversity in African populations, and supports the existence of novel population substructure in the Late Middle Paleolithic. Our results indicate that our species' demographic history around the out-of-Africa event is more complex than previously appreciated.
    YFull: YF14620 (Dante Labs 2018)

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    The First complete Zoroastrian-Parsi Mitochondria Reference Genome: ...

    The First complete Zoroastrian-Parsi Mitochondria Reference Genome: Implications of mitochondrial signatures in an endogamous, non-smoking population
    Villoo Morawala-Patell, Naseer Shaik Pasha, Kashyap Krishnasamy, Bharti Mittal, Chellappa Gopalakrishnan, Raja Mugasimangalam, Naveen Sharma, Arati Khanna-Gupta, Perviz Bhote-Patell, Sudha N. Rao, Renuka Jain

    Abstract
    The present-day Zoroastrian-Parsis have roots in ancient pastoralist migrations from circumpolar regions leading to their settlement on the Eurasian Steppes and later, as Indo Iranians in the Fertile Crescent. From then, the Achaemenids (550 - 331 BC), and later the Sassanids (224 BC - 642 AD) established the mighty Persian Empires. The Arab invasion of Persia in 642 AD necessitated the migration of Zoroastrians from Pars to India where they settled as Parsis and practiced their faith, Zoroastrianism. Endogamy became a dogma, and the community has maintained the practice since their arrival in India. Fire is the medium of worship as it is considered pure and sacrosanct; Social ostracism practiced against smokers resulted in a non-smoking community, thus forming a unique basis for our study. In order to gain a clearer understanding of the historically recorded migration of the Zoroastrian-Parsis, decipher their phylogenetic relationships and understand disease association to their individual mitochondrial genomes, we generated the first complete de novo Zoroastrian-Parsi Mitochondrial Reference Genome, AGENOME-ZPMS-HV2a-1. Phylogenetic analysis of additional 100 Parsi mitochondrial genome sequences, showed their distribution into 7 major haplogroups and 25 sub-haplogroups and a largely Persian origin for the Parsi community. We have generated individual reference genomes for each major haplogroup and assembled the Zoroastrian Parsi Mitochondrial Consensus Genome (AGENOME-ZPMCG V1.0) for the first time in the world. We report 420 variants, specifically 12 unique mitochondrial variants in the 100 mitochondrial genome sequences compared with the revised Cambridge Reference Sequence (rCRS) standard. Disease association mapping showed 217 unique variants linked to longevity and 41 longevity associated disease phenotypes across most haplogroups. Our results indicate none of the variants are linked to lung cancer. Mutational signatures, C>A, G>T transitions, linked to tobacco carcinogens were found at extremely low frequencies in the Zoroastrian-Parsi cohort. Our analysis of gene-coding, tRNA and the D-Loop regions revealed haplogroup specific disease associations for Parkinsons, Alzheimers, Cancers, and Rare diseases. These disease signatures investigated in the backdrop of generations of endogamy, in the rapidly declining, endangered Zoroastrian-Parsi community of India, provides exceptional universal opportunity to understand and mitigate disease.
    YFull: YF14620 (Dante Labs 2018)

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  9. #1295
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    DNA is the key to unlocking our ancient African past
    Alexandra Coutinho; Mário Vicente; Carina Schlebusch

    Each region of the world, and the human groups living in them, have unique histories of migration, genetic mixing (admixture) and adaptation that have shaped their past. While archaeology has been of extreme value in elucidating this complex, multifaceted past, the genesis of DNA studies has enriched their story, and now ancient DNA (aDNA) has helped answer even more questions surrounding our prehistory. aDNA offers a unique opportunity to access genetic variation of past populations and enables us to contextualize past populations in present-day genetic variation. By linking the past to the present in this way, we now have a deeper understanding of our prehistory, and how our genetic landscape has changed from the past to the present. However, the study of aDNA is complex and there are various factors that need to be considered to yield successful aDNA results.

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    Thread here - https://anthrogenica.com/showthread....ction-and-repl

    Ancient genomes reveal complex patterns of population movement, interaction, and replacement in sub-Saharan Africa
    Ke Wang et al. Johannes Krause

    Abstract
    Africa hosts the greatest human genetic diversity globally, but legacies of ancient population interactions and dispersals across the continent remain understudied. Here, we report genome-wide data from 20 ancient sub-Saharan African individuals, including the first reported ancient DNA from the DRC, Uganda, and Botswana. These data demonstrate the contraction of diverse, once contiguous hunter-gatherer populations, and suggest the resistance to interaction with incoming pastoralists of delayed-return foragers in aquatic environments. We refine models for the spread of food producers into eastern and southern Africa, demonstrating more complex trajectories of admixture than previously suggested. In Botswana, we show that Bantu ancestry post-dates admixture between pastoralists and foragers, suggesting an earlier spread of pastoralism than farming to southern Africa. Our findings demonstrate how processes of migration and admixture have markedly reshaped the genetic map of sub-Saharan Africa in the past few millennia and highlight the utility of combined archaeological and archaeogenetic approaches.
    https://advances.sciencemag.org/content/6/24/eaaz0183

    Table S10. The mitochondrial and Y chromosome haplogroups in all currently available ancient African genomes
    Here we summarise the uniparental haplogroup information for every ancient genetic cluster observed in PCA.

    Genetic Cluster Site Lab ID Genetic ID Sex mtDNA haplogroup Y Haplogroup Publication mtDNA hapl. used for plot Y hapl. used for plot
    east Afr. Foragers Nyarindi Rockshelter NYA002 Kenya_Nyarindi_3500BP F L4b2a .. This Study L4b
    east Afr. Foragers Nyarindi Rockshelter NYA003 Kenya_Nyarindi_3500BP M .. E This Study .. E
    east Afr. Pastoralists Lukenya Hill, GvJm 202 LUK001 Kenya_LukenyaHill_3500BP M L4b2a2b E1b1b1b2b This Study L4b E1b1b1b2b
    east Afr. Pastoralists Lukenya Hill, GvJm 202 LUK003 Kenya_LukenyaHill_3500BP F L0f1 .. This Study L0f
    east Afr. Pastoralists Hyrax Hill, GrJj25 HYR002 Kenya_HyraxHill_2300BP M L5a1b E1b1b1b2b This Study L5a E1b1b1b2b
    east Afr. Pastoralists Molo Cave, GoJi3 MOL001 Kenya_MoloCave_1500BP M L3h1a2a1 E1b1b1b2b This Study L3h E1b1b1b2b
    east Afr. Pastoralists Molo Cave, GoJi3 MOL003 Kenya_MoloCave_1500BP F .. .. This Study ..
    east Afr. Foragers Kakapel KPL001 Kenya_Kakapel_3900BP M L3i1 CT This Study L3i CT
    east Afr. Iron Age Kakapel KPL002 Kenya_Kakapel_300BP F L2a1f .. This Study L2a
    east Afr. Iron Age Kakapel KPL003 Kenya_Kakapel_900BP F L2a5 .. This Study L2a
    Bantu-related Munsa MUN001* Uganda_Munsa_500BP F L3b1a1 .. This Study L3b
    Bantu-related Kindoki KIN002 Congo_Kindoki_230BP M L1c3a1b E1b1a1a1d1a2 This Study L1c E1b1a1a1d1a2
    Bantu-related Kindoki KIN003 Congo_Kindoki_150BP M .. E This Study .. E
    Bantu-related Kindoki KIN004 Congo_Kindoki_230BP M L0a1b1a1 R1b1 This Study L0a R1b1
    Bantu-related Ngongo Mbata NGO001 Congo_NgongoMbata_220BP M L1c3a .. This Study L1c
    east Afr. Iron Age Matangai Turu Northwest MTN001 Congo_MatangaiTuru_750BP F .. .. This Study ..
    south Afr. Foragers/Bantu-related Nqoma NQO002* Botswana_Nqoma_900BP F L2a1f .. This Study L2a
    south Afr. Foragers/Bantu-related Taukome TAU001* Botswana_Taukome_1100BP M L0d3b1 E1b1a1 This Study L0d E1b1a1
    south Afr. Foragers/Bantu-related Xaro XAR001* Botswana_Xaro_1400BP M L3e1a2 E1b1a1a1c1a This Study L3e E1b1a1
    south Afr. Foragers/Bantu-related Xaro XAR002* Botswana_Xaro_1400BP M L0k1a2 E1b1b1b2b This Study L0k E1b1b1
    east Afr. Foragers White Rock Point (GrJb2) I8931 Kenya_LSA F L0a2 - Prendergastetal2019 L0a
    east Afr. Foragers White Rock Point (GrJb2) I8930 Kenya_LSA M L2a4 BT(xCT) Prendergastetal2019 L2a BT
    east Afr. Pastoralists Rigo Cave (GrJh3) I8923 Kenya_Pastoral_Neolithic_Elmenteitan M M1a1b E1b1b1b2b2 Prendergastetal2019 M1a E1b1b1b2b
    east Afr. Pastoralists Rigo Cave (GrJh3) I8922 Kenya_Pastoral_Neolithic_Elmenteitan M L4b2a2c E1b1b1b2b2a1 Prendergastetal2019 L4b E1b1b1b2b
    east Afr. Pastoralists Naivasha Burial Site I8920 Kenya_Pastoral_Neolithic M L3h1a1 E1b1b1b2b2a1 Prendergastetal2019 L3h E1b1b1b2b
    east Afr. Pastoralists Naivasha Burial Site I8919 Kenya_Pastoral_Neolithic M L4a1 A1b1b2b Prendergastetal2019 L4a A1b
    east Afr. Pastoralists Naivasha Burial Site I8918 Kenya_Pastoral_Neolithic M L3x1a E1b1b1b2b2a1 Prendergastetal2019 L3x E1b1b1b2b
    east Afr. Iron Age Kokurmatakore Cairn 2 (GdJn 2) I8904 Kenya_Pastoral_IA_Possible M L3a2a E1b1b1(xE1b1b1b2b) Prendergastetal2019 L3a E1b1b1
    east Afr. Iron Age Kisima Farm, Cairn KFR-C4 I8901 Kenya_Pastoral_IA M L3h1a1 E2(xE2b) Prendergastetal2019 L3h E2
    east Afr. Iron Age Ilkek Mounds/Ilkek II (Gilgil) (GsJj66) I8892 Kenya_Pastoral_IA M L0f2a E2(xE2b) Prendergastetal2019 L0f E2
    east Afr. Pastoralists Cole's Burial (GrJj5a) I8874 Kenya_Pastoral_Neolithic M L3i2 E1b1b1a1a1b1 Prendergastetal2019 L3i E1b1b1a1a
    east Afr. Pastoralists Naivasha Burial Site I8830 Kenya_Pastoral_Neolithic M M1a1b xBT Prendergastetal2019 M1a xBT
    east Afr. Pastoralists Kisima Farm A5 (Porcupine Cave) I8820 Kenya_Pastoral_Neolithic F M1a1f - Prendergastetal2019 M1a
    east Afr. Pastoralists Naivasha Burial Site I8814 Kenya_Pastoral_Neolithic F L4b2a2b - Prendergastetal2019 L4b
    east Afr. Pastoralists Kisima Farm A5 (Porcupine Cave) I8809 Kenya_Pastoral_Neolithic M M1a1 E1b1b1b2b2a1 Prendergastetal2019 M1a E1b1b1b2b
    east Afr. Foragers Jawuoyo Rockshelter I8808 Kenya_LSA M L4b2a2c E1b1b1a1b2 Prendergastetal2019 L4b E1b1b1
    east Afr. Pastoralists Egerton Cave (GrJh10) I8805 Kenya_Pastoral_Neolithic_Elmenteitan F L0a1d - Prendergastetal2019 L0a
    east Afr. Pastoralists Keringet Cave (GrJg4)? 1 I8804 Kenya_Pastoral_Neolithic M L4b2a1 A1b1b2 Prendergastetal2019 L4b A1b
    east Afr. Iron Age Deloraine Farm (GqJh6) I8802 Kenya_IA_Deloraine M L5b1 E1b1a1a1a1a Prendergastetal2019 L5b E1b1a1
    east Afr. Pastoralists Naishi Rockshelter I8759 Kenya_Pastoral_Neolithic_outlier M L3x1a E1b1b1b2b Prendergastetal2019 L3x E1b1b1b2b
    east Afr. Pastoralists Naishi Rockshelter I8758 Kenya_Pastoral_Neolithic M L0a2d A1b(xA1b1b2a) Prendergastetal2019 L0a A1b
    east Afr. Foragers Gishimangeda Cave I13983 Tanzania_PN_Forager M L4b2a2 BT(xCT) Prendergastetal2019 L4b BT
    east Afr. Foragers Gishimangeda Cave I13982 Tanzania_PN_Forager F .. - Prendergastetal2019 ..
    east Afr. Pastoralists Gishimangeda Cave I13981 Tanzania_PN F L0a - Prendergastetal2019 L0a
    east Afr. Pastoralists Gishimangeda Cave I13980 Tanzania_PN M HV1b1 E1b1b1a1b2 Prendergastetal2019 HV1 E1b1b1a1b
    east Afr. Pastoralists Gishimangeda Cave I13979 Tanzania_PN F L3x1 - Prendergastetal2019 L3x
    east Afr. Pastoralists Gishimangeda Cave I13978 Tanzania_PN_outlier F L4b2a1 - Prendergastetal2019 L4b
    east Afr. Pastoralists Gishimangeda Cave I13977 Tanzania_PN M L0f2a1 E1b1b1b2b2 Prendergastetal2019 L0f E1b1b1b2b
    east Afr. Pastoralists Gishimangeda Cave I13972 Tanzania_PN_outlier M T2+150 E1b1b1b2b2 Prendergastetal2019 T2+ E1b1b1b2b
    east Afr. Pastoralists Gishimangeda Cave I13970 Tanzania_PN_Data_Questionable F L3h1a2a1 - Prendergastetal2019 L3h
    east Afr. Foragers Gishimangeda Cave I13763 Tanzania_PN_Forager F .. - Prendergastetal2019 ..
    east Afr. Pastoralists Gishimangeda Cave I13762 Tanzania_PN M L3i2 E1b1b1b2b2a1 Prendergastetal2019 L3i E1b1b1b2b
    east Afr. Pastoralists Prettejohn's Gully (GsJi11) I12534 Kenya_Early_Pastoral_N F L3f1b - Prendergastetal2019 L3f
    east Afr. Pastoralists Prettejohn's Gully (GsJi11) I12533 Kenya_Early_Pastoral_N M K1a E2(xE2b) Prendergastetal2019 K1a E2
    east Afr. Pastoralists Rigo Cave (GrJh3) I12398 Kenya_Pastoral_Neolithic_Elmenteitan M L3f E1b1b1b2b2a1 Prendergastetal2019 L3f E1b1b1b2b
    east Afr. Pastoralists Keringet Cave (GrJg4) I12394 Kenya_Pastoral_Neolithic_Elmenteitan F K1a - Prendergastetal2019 K1a
    east Afr. Pastoralists Kasiole 2 burial (GvJh54) I12391 Kenya_Pastoral_IA_Data_Questionable U L3h1a2a1 E1b1b1b2b Prendergastetal2019 L3h E1b1b1b2b
    east Afr. Pastoralists Ol Kalou I12384 Kenya_Pastoral_Neolithic M L3d1d E1b1b1b2b2a1 Prendergastetal2019 L3d E1b1b1b2b
    east Afr. Iron Age Laikipia District Burial Site (GoJl45) I12381 Kenya_Pastoral_IA F L0a1c1 - Prendergastetal2019 L0a
    east Afr. Iron Age Emurula Ole Polos Cairns (GvJh122) I12379 Kenya_Pastoral_IA M L3h1a2a1 E1b1b1b2b2a1 Prendergastetal2019 L3h E1b1b1
    east Afr. Pastoralists Njoro River Cave II I10719 Kenya_Pastoral_Neolithic_Elmenteitan F L3h1a2a1 - Prendergastetal2019 L3h
    south Afr. Foragers Faraoskop Rock Shelter UCT386 South_Africa_2000BP M .. A1b1b2a SkoglundCell2017 .. A1b1b2
    south Afr. Foragers Kasteelberg UCT473 South_Africa_1200BP F .. .. SkoglundCell2017 ..
    south Afr. Foragers St. Helena KhoesanLeipzigHunter South_Africa_2000BP M .. A1b1b2a SkoglundCell2017 .. A1b1b2
    east Afr. Foragers Panga ya Saidi, Kilifi District I0595 Kenya_400BP M L4b2a2 E1b1b1b2 SkoglundCell2017 L4b E1b1b1
    east Afr. Foragers Mapangani Cave, Pemba Island, Zanzibar Archipelago I1048 Tanzania_Pemba_1400BP F L0a1'4 .. SkoglundCell2017 L0a
    east Afr. Foragers Kuumbi Cave, Zanzibar I0589 Tanzania_Zanzibar_1300BP F L4b2a2 .. SkoglundCell2017 L4b
    east Afr. Pastoralists Luxmanda, UVS40 I3726 Tanzania_Luxmanda_3100BP F L2a1 .. SkoglundCell2017 L2a
    Bantu-related Mapangani Cave, Pemba Island, Zanzibar Archipelago I2298 Tanzania_Pemba_600BP F L2a1a2 .. SkoglundCell2017 L2a
    south Afr. Foragers Hora I2966 Malawi_Hora_8100BP M .. BT(xCT) SkoglundCell2017 .. BT
    south Afr. Foragers Hora I2967 Malawi_Hora_8100BP F L0a2 .. SkoglundCell2017 ..
    south Afr. Foragers Fingira I4468 Malawi_Fingira_6100BP M L0d1c BT(xCT) SkoglundCell2017 L0d BT
    south Afr. Foragers Fingira I4427 Malawi_Fingira_6100BP M L0d1b2b BT(xCT) SkoglundCell2017 L0d BT
    south Afr. Foragers Chencherere I4421 Malawi_Chencherere_5200BP F L0k2 .. SkoglundCell2017 L0k
    south Afr. Foragers Chencherere I4422 Malawi_Chencherere_5200BP F L0k1 .. SkoglundCell2017 L0k
    south Afr. Foragers Fingira I4426 Malawi_Fingira_2500BP F L0f .. SkoglundCell2017 L0f
    south Afr. Foragers Ballito Bay baa001.SG South_Africa_2000BP M L0d2c1 A1b1b2a Schlebusch et al 2017 L0d2 A1b1b2
    south Afr. Foragers Ballito Bay bab001.SG South_Africa_2000BP M L0d2a1 A1b1b2 Schlebusch et al 2017 L0d2 A1b1b2
    south Afr. Foragers/Bantu-related Champagne Castle cha001.SG South_Africa_400BP F L0d2a1a .. Schlebusch et al 2017 L0d2
    south Afr. Foragers Doonside doo001.SG South_Africa_2000BP U L0d2 A Schlebusch et al 2017 L0d2 A
    south Afr. Foragers/Bantu-related Eland Cave ela001.SG South_Africa_400BP F L3e3b1 .. Schlebusch et al 2017 L3e
    south Afr. Foragers/Bantu-related Mfongosi mfo001.SG South_Africa_400BP F L3e1b2 .. Schlebusch et al 2017 L3e
    south Afr. Foragers/Bantu-related Newcastle new001.SG South_Africa_400BP F L3e2b1a2 .. Schlebusch et al 2017 L3e
    Last edited by RCO; 06-15-2020 at 11:43 PM.
    J1 FGC5987 to FGC6175 (188 new SNPs)
    MDKAs before Colonial Brazil
    Y-DNA - Milhazes, Barcelos, Minho, Portugal.
    mtDNA - Ilha Terceira, Azores, Portugal
    North_Swedish + PT + PT + PT @ 3.96 EUtest 4

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  13. #1297
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    Australia Italy Veneto Friuli Italy Trentino Alto Adige Italy Ladinia Austria Tirol
    https://reich.hms.harvard.edu/sites/...00264-main.pdf

    Contents lists available at Science Direct Quaternary International journal homepage:www.elsevier.com/locate/quaintLate Upper Palaeolithic hunter-gatherers in the Central Mediterranean: New archaeological and genetic data from the Late Epigravettian burial Oriente C(Favignana, Sicily)

    Giulio Catalanoa, Domenico Lo Vetrob, Pier Francesco Fabbri, Swapan Mallicke,David Reich, Nadin Rohlande, Luca Sineoa, Iain Mathiesonh, Fabio Martini

    Here we generated new genome-wide data in order to refine the genetic affinities of Oriente C to other European hunter-gatherer populations. Our results and additional population genetic analyses provide insights into the origin and population structure of the hunter-gatherers that inhabited Europe during the Late Upper Palaeolithic and Mesolithic.
    Last edited by vettor; 06-19-2020 at 05:19 PM.


    My Path = ( K-M9+, TL-P326+, T-M184+, L490+, M70+, PF5664+, L131+, L446+, CTS933+, CTS3767+, CTS8862+, Z19945+ )


    Grandfather via paternal grandmother = I1-L22 ydna
    Great grandmother paternal side = T1a1e mtdna

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  15. #1298
    Registered Users
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    319
    Location
    USA
    Y-DNA (P)
    H-Z4417
    mtDNA (M)
    M3d

    https://www.nature.com/articles/s41598-020-66953-3

    Novel insights on demographic history of tribal and caste groups from West Maharashtra (India) using genome-wide data

    Guilherme Debortoli, Cristina Abbatangelo, Francisco Ceballos, Cesar Fortes-Lima, Heather L. Norton, Shantanu Ozarkar, Esteban J. Parra & Manjari Jonnalagadda

    Abstract
    The South Asian subcontinent is characterized by a complex history of human migrations and population interactions. In this study, we used genome-wide data to provide novel insights on the demographic history and population relationships of six Indo-European populations from the Indian State of West Maharashtra. The samples correspond to two castes (Deshastha Brahmins and Kunbi Marathas) and four tribal groups (Kokana, Warli, Bhil and Pawara). We show that tribal groups have had much smaller effective population sizes than castes, and that genetic drift has had a higher impact in tribal populations. We also show clear affinities between the Bhil and Pawara tribes, and to a lesser extent, between the Warli and Kokana tribes. Our comparisons with available modern and ancient DNA datasets from South Asia indicate that the Brahmin caste has higher Ancient Iranian and Steppe pastoralist contributions than the Kunbi Marathas caste. Additionally, in contrast to the two castes, tribal groups have very high Ancient Ancestral South Indian (AASI) contributions. Indo-European tribal groups tend to have higher Steppe contributions than Dravidian tribal groups, providing further support for the hypothesis that Steppe pastoralists were the source of Indo-European languages in South Asia, as well as Europe.

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  17. #1299
    Registered Users
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    Sex
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    Y-DNA (P)
    J1a1 FGC6064+ M365+
    mtDNA (M)
    H1ao1

    Suebi Kingdom Portugal 1143 Portugal 1485 Portugal Order of Christ Brazilian Empire Brazil
    Whole genomes reveal severe bottleneck among Asian hunter-gatherers following the invention of agriculture
    Saikat Chakraborty, Analabha Basu, GenomeAsia 100K Consortium

    doi: https://doi.org/10.1101/2020.06.25.170308

    Abstract
    The invention of agriculture (IOA) by anatomically modern humans (AMH) around 10,000 years before present (ybp) is known to have led to an increase in their carrying capacity and hence its population size. Reconstruction of historical demography using high coverage (~30X) whole genome sequences (WGS) from >700 individuals from different South Asian (SAS) and Southeast Asian (SEA) populations reveals that although several present day populous groups did indeed experience a positive Neolithic Demographic Transition (NDT), most hunter-gatherers (HGs) experienced a demographic decrease. Differential fertility between HGs and non-HGs, exposure of HGs to novel pathogens from non-HGs could have resulted in such contrasting patterns. However, we think the most parsimonious explanation of the drastic decrease in population size of HGs is their displacement/enslavement by non-HGs.
    https://www.biorxiv.org/content/10.1...06.25.170308v1
    J1 FGC5987 to FGC6175 (188 new SNPs)
    MDKAs before Colonial Brazil
    Y-DNA - Milhazes, Barcelos, Minho, Portugal.
    mtDNA - Ilha Terceira, Azores, Portugal
    North_Swedish + PT + PT + PT @ 3.96 EUtest 4

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  19. #1300
    Registered Users
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    J1a1 FGC6064+ M365+
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    H1ao1

    Suebi Kingdom Portugal 1143 Portugal 1485 Portugal Order of Christ Brazilian Empire Brazil
    Geographical structuring and low diversity of paternal lineages in Bahrain shown by analysis of 27 Y-STRs
    Noora R. Al-Snan, Safia A. Messaoudi, Yahya M. Khubrani, Jon H. Wetton, Mark A. Jobling & Moiz Bakhiet
    Molecular Genetics and Genomics (2020)
    Original Article
    Open Access
    Published: 25 June 2020

    Abstract
    We have determined the distribution of Y-chromosomal haplotypes and predicted haplogroups in the ethnically diverse Kingdom of Bahrain, a small archipelago in the Arabian Gulf. Paternal population structure within Bahrain was investigated using the 27 Y-STRs (short tandem repeats) in the Yfiler Plus kit to generate haplotypes from 562 unrelated Bahraini males, sub-divided into four geographical regions—Northern, Capital, Southern and Muharraq. Yfiler Plus provided a significant improvement over the 17-locus Yfiler kit in discrimination capacity (from 77% to 87.5% overall), but discrimination capacity differed widely between regions from 98.4% in Muharraq to 75.2% in the Northern region, an unusually low value possibly resulting from recent rapid population expansion. Clusters of closely related male lineages were seen, with only 79.4% of donors displaying unique haplotypes and 59% of instances of shared haplotypes occurring within, rather than between, regions. Haplogroup prediction indicated diverse origins of the population with a predominance of haplogroups J2 and J1, both typical of the Arabian Peninsula, but also haplogroups such as B2 and E1b1a likely originating in Africa, and H, L and R2 likely indicative of migration from South Asia. Haplogroup frequencies differed significantly between regions, with J2 significantly more common in the Northern region compared with the Southern, possibly due to differential settlement by Baharna and Arabs. Our study shows that paternal lineage population structure can exist even over small geographical scales, and that highly discriminating genetic tools are required where rapid expansions have occurred within tightly bounded populations.
    https://link.springer.com/article/10...38-020-01696-4
    J1 FGC5987 to FGC6175 (188 new SNPs)
    MDKAs before Colonial Brazil
    Y-DNA - Milhazes, Barcelos, Minho, Portugal.
    mtDNA - Ilha Terceira, Azores, Portugal
    North_Swedish + PT + PT + PT @ 3.96 EUtest 4

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     J Man (07-02-2020),  Patarames (06-30-2020),  Reza (06-30-2020),  vishankar (06-30-2020)

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