mtDNA Perfect Matches

[Ian B]

I know that mtDNA H is a very common and widespread European haplogroup, but why am I getting so many "perfect matches"?
And why of all the perfect matches are none apparently related to me?
Where did my mitochondrial "Eve" originate? Or, more precisely, when where was my Eve first found In Europe?

[GailT]

Do you have any extra mutations, or are you plain H2a2 with no extras? H2a2 is estimated to be about 9000 years old, but if you have extra mutations you should be part of a younger subclade.

Gail T

[Ian B]

Do you have any extra mutations, or are you plain H2a2 with no extras? H2a2 is estimated to be about 9000 years old, but if you have extra mutations you should be part of a younger subclade.

Gail T

@Gail: HVR 1

	Location	Mutation Type	Nucleotide Change
	16519	Substitution	T > c

and at HVR2:

	Location	Mutation Type	Nucleotide Change
	263	Substitution	A > g
	315	Insertion	C > CC

I arrived at H2A2 by checking the above against the chart.

Did I make a mistake?

[GailT]

You would need the coding region results from the full mtDNA genome to identify a specific subclade of H. H2a2 is one possibility but there are people in many other subclades of H that also match your results.

[AJL]

Moved to mtDNA H and merged with several posts deleted to remove duplication.

[Ian B]

Gail:

Is this what you mean?
HVR 1

16001
ATTCTAATTT AAACTATTCT CTGTTCTTTC ATGGGGAAGC AGATTTGGGT
16051
ACCACCCAAG TATTGACTCA CCCATCAACA ACCGCTATGT ATTTCGTACA
16101
TTACTGCCAG CCACCATGAA TATTGTACGG TACCATAAAT ACTTGACCAC
16151
CTGTAGTACA TAAAAACCCA ATCCACATCA AAACCCCCTC CCCATGCTTA
16201
CAAGCAAGTA CAGCAATCAA CCCTCAACTA TCACACATCA ACTGCAACTC
16251
CAAAGCCACC CCTCACCCAC TAGGATACCA ACAAACCTAC CCACCCTTAA
16301
CAGTACATAG TACATAAAGC CATTTACCGT ACATAGCACA TTACAGTCAA
16351
ATCCCTTCTC GTCCCCATGG ATGACCCCCC TCAGATAGGG GTCCCTTGAC
16401
CACCATCCTC CGTGAAATCA ATATCCCGCA CAAGAGTGCT ACTCTCCTCG
16451
CTCCGGGCCC ATAACACTTG GGGGTAGCTA AAGTGAACTG TATCCGACAT
16501
CTGGTTCCTA CTTCAGGGcC ATAAAGCCTA AATAGCCCAC ACGTTCCCCT
16551
TAAATAAGAC ATC

[Ian B]

Gail-

PANEL HVR2

1
GATCACAGGT CTATCACCCT ATTAACCACT CACGGGAGCT CTCCATGCAT
51
TTGGTATTTT CGTCTGGGGG GTATGCACGC GATAGCATTG CGAGACGCTG
101
GAGCCGGAGC ACCCTATGTC GCAGTATCTG TCTTTGATTC CTGCCTCATC
151
CTATTATTTA TCGCACCTAC GTTCAATATT ACAGGCGAAC ATACTTACTA
201
AAGTGTGTTA ATTAATTAAT GCTTGTAGGA CATAATAATA ACAATTGAAT
251
GTCTGCACAG CCgCTTTCCA CACAGACATC ATAACAAAAA ATTTCCACCA
301
AACCCCCCCT CCCCC*GCTTC TGGCCACAGC ACTTAAACAC ATCTCTGCCA
351
AACCCCAAAA ACAAAGAACC CTAACACCAG CCTAACCAGA TTTCAAATTT

[geebee]

Technically, I would have to say I don't have any "perfect" matches. I have exactly one match that includes HV1, HVR2, and the Coding Region, and even that match has a GD of 3. This match only appeared as of the beginning of this month.

However, I also have one match that would probably be a perfect match if the other individual had taken the FGS. Since he didn't, the match only shows up when don't include the Coding Region. But I say it's "probably" a perfect match because it turns out to be to the same most distant known mtDNA ancestor. She's a 6th great grandmother to me, and I think to my cousin as well; but we actually both descend from the same daughter as well.

And this ancestry is located in a branch that, for both me and for my cousin, is very intertwined. Nothing illegal, though at least some folks would still probably be squicked. It includes at least one marriage of "first cousins, once removed", and maybe a couple of second cousin marriages.

I'm in the process of finding out from my cousin what other tests he might have taken. I'd certainly like to be able to compare the results of any autosomal testing, since it looks as if we're related in multiple ways.

[geebee]

"...why of all the perfect matches are none apparently related to me?"

They're all related to you. But mtDNA isn't very useful for finding close enough matches to be "genealogically meaningful". It changes too slowly.

This page (http://www.mtdnacommunity.org/human-...phylogeny.aspx), shows what's probably just about the most current mtDNA phylotree. My own haplogroup of H1bg shows only two samples, one of which is my own.

Unfortunately, it also means it isn't all that useful for trying to pinpoint origin. The other sample's "earliest known mtDNA ancestor" was from Romania, while mine was born in southern Mississippi. However, the birth year for the Romanian-born ancestor was not until something like 1912. For the Mississippi-born ancestor (who was of French descent), it was more like 1730.

But, again, mtDNA is not particularly useful for finding close relatives. I happened to find one -- or he found me -- but it was more because we happened to have listed the very same woman as our earliest mtDNA ancestor.

[Historian]

Anyone know where H1a is most common? I received Scandinavian results for my H1a mtDNA results and
I only know a little ancestry on my maternal side (German, Polish, and Swiss). Thanks.