Y-haplogroup R1b is associated with an increased risk of recurrent venous thrombosis

[R.Rocca]

I found this by chance while searching for some other R1b related paper:

Y-haplogroup R1b is associated with an increased risk of recurrent venous thrombosis in men

http://www.nvth.nl/bijlagen/FinalprogrammeNVTH2013.pdf

My father had a blood clot in his leg when he got off of a 12 hour flight last year. The doctors caught it in time, but scary stuff.

[Jean M]

If you have been tested by 23andMe, you can check your own risk level. Mine is higher than average, so the advice is to make sure you move around on long-haul flights and indeed in general. Plus the surgeon will want to know ahead of certain types of surgery. An ounce of prevention ...

[TigerMW]

I found this by chance while searching for some other R1b related paper:

Y-haplogroup R1b is associated with an increased risk of recurrent venous thrombosis in men

http://www.nvth.nl/bijlagen/FinalprogrammeNVTH2013.pdf

My father had a blood clot in his leg when he got off of a 12 hour flight last year. The doctors caught it in time, but scary stuff.

I'm glad the doctors were able to help your father.

My father hasn't had any problems like that but my grandfather died in his sixties due to a stroke, which is a blood clot to the brain.

I'm not sure if my grandfather's stroke is the reason, but my doctor has had me take high doses of omega-3 capsules for a couple of years and this is supposed to help.

Omega-3 fatty acids may decrease triglycerides, lower blood pressure, reduce blood clotting, boost immunity and improve arthritis symptoms, and in children may improve learning ability. Eating one to two servings a week of fish, particularly fish that's rich in omega-3 fatty acids, appears to reduce the risk of heart disease, particularly sudden cardiac death

. http://www.mayoclinic.com/health/omega-3/HB00087

[alan]

I wonder if this applies for every country? Or could this just be a result of many R1b people coming from western Europe.

[Jean M]

Just what I was thinking Alan. There surely can't be any functional connection between the haplogroup and venous thrombosis.

[alan]

Just what I was thinking Alan. There surely can't be any functional connection between the haplogroup and venous thrombosis.

One would hope that they have had the sense not to imply a causal rather than apparent link without these kind of checks but I wouldnt be surprised. They would need to compare R1b men with non-R1b men within the same geography, historic period ancestry and subculture. As you know R1b is an eastern originated clade now found mostly in the Atlantic west among peoples who autosomally cluster either with northern Europeans (as is the case in the isles) and among populations who autosomally cluster with Med. people (Spanish, Italians). I find a yDNA link really unlikely although I could be wrong.

[R.Rocca]

There was a study a few years back that linked haplogroup I and heart disease a few years back, but 23andMe didn't find it all that convincing, although they didn't rule it out all together. Here is their take on it...

http://blog.23andme.com/news/second-...heart-disease/

[DMXX]

Thread moved to Medical Genetics.