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Thread: rs6311 (Serotonin)

  1. #1
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    Mameluke

    rs6311 (Serotonin)

    TT is associated with depression, panic disorder, and a higher stress response.
    The T allele was associated with a reduction in general health, vitality, and social
    function (p=0.0031-0.040) (R).

    The T allele is associated with IBS (R) and CFS (R).

    The C allele is associated with an extraverted personality, rheumatoid Arthritis and novelty seeking.

    https://selfhacked.com/2016/02/12/5h...lems-and-cirs/

    Can you guys & gals post your alleles & report if there is any family history of psych problems? TT here, I had apathy and mild depression but it's being successfully treated with psilocybin mushrooms.

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  3. #2
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    I am CC. I have long term psychiatric problems including depression,general and social anxiety, mood swings and paranoia. I have always been introverted and shy. I don't respond well to stress and tend to experience a decline in cognitive functioning when stressed.
    Last edited by firemonkey; 12-14-2016 at 06:09 AM.
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  5. #3
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    Quote Originally Posted by firemonkey View Post
    I am CC. I have long term psychiatric problems including depression,general and social anxiety, mood swings and paranoia. I have always been introverted and shy. I don't respond well to stress and tend to experience a decline in cognitive functioning when stressed.
    me also .....
    best regarards
    adam


    p.s
    i checked my now in ftdna raw data
    TC
    Last edited by kingjohn; 12-14-2016 at 04:36 PM.

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  7. #4
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    In my group:

    3 TT - 2 with anxiety disorders including panic attacks, history of debilitating depression. The third one is more resilient but is very religious, which I think is a form of self-medicating for his anxiety and depression.

    4 CT - All have anxiety issues with periods of depression, not debilitating, and in my case, panic attacks.

    1 CC - Is anxious but is also known as being an extreme magical thinker, which she uses to distance herself from her problems and scary emotions.
    My Gedmatch kits: M102536 (v3 upgrade); M054852 (v2); A449981 (Ancestry v1)
    Known: 87.5% UK/Ireland American Colonial; 12.5% PA Dutch Mennonites from Germany & Switzerland
    J1c3i mitochondrial ancestress was Swiss Mennonite from Conestoga, Lancaster PA

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    All CTs in my group.

    I had a brief bit of environmental depression a long time ago after a sudden death in the family, but no lingering issues. Medium-extroverted and don't have rheumatoid arthritis (which my maternal great-grandmother had), IBS, or CFS. I'd put myself somewhere between conservative and novelty-seeking.

    My grandfather was CT and had periods of deep depression despite being highly extroverted; he also had tendencies to OCD.
     

    Other ancestral Y lines:

    E1b-M81 Ukraine (Ashkenazi)
    E1b-V13 England
    I1-M253 Ireland
    I2-M423 Ukraine
    R1a-L176.1 Scotland
    R1b-L584 Syria/Turkey (Sephardi)
    R1b-L20 Ireland
    R1b-L21 (1)England; (2)Wales?>Connecticut
    R1b-L48 England
    R1b-P312 Scotland
    R1b-FGC32576 Ireland

    Other ancestral mtDNA lines:

    H1b2a Ukraine (Ashkenazi)
    H6a1a3 Ukraine
    K1a9 Belarus (Ashkenazi)
    K1c2 Ireland
    V7a Ukraine

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    Quote Originally Posted by Asparuk View Post
    https://selfhacked.com/2016/02/12/5h...lems-and-cirs/

    Can you guys & gals post your alleles & report if there is any family history of psych problems? TT here, I had apathy and mild depression but it's being successfully treated with psilocybin mushrooms.
    Why do you want to know? Why bring my family into it? Is there something you know about them? What's with the mushrooms? You trying for mind control? I noticed you lurking, are you following me? PAUSE!

    Forgot my Meds, feel better now. You guys got issues. I'm out of here. Doc says keep projecting the image of stability. I'm not crazy, I'm not crazy.

    Oh ye, C/T

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    Smile

    TC for me. Both my dad and mom have TC, as well.

    Pretty happy generally. We all have our down days though.

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    TT here, Mother is debilitating depressive but CT. Me, well I can feel depressed from time to time but never to the state where I stay in bed for days.

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    Wink

    I think I must be doing pretty good on Serotonin with my TC, because most of the time I feel pretty damn good, and that despite some crap in my life that would curl your hair.

    Or is it alcohol?

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    Quote Originally Posted by rms2 View Post
    I think I must be doing pretty good on Serotonin with my TC, because most of the time I feel pretty damn good, and that despite some crap in my life that would curl your hair.

    Or is it alcohol?
    I think the best antidepressant medication in your case is a new paper about ancient dna haha.

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