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Thread: Genetic Genealogy and Ancient DNA in the News

  1. #2431
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    https://www.stitcher.com/podcast/insitome/the-insight

    Today on The Insight Razib talks to Lara Cassidy about the genetic history of the Irish #Genetics

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    “Then 4,500 years ago the Beaker people arrived in Britain and Ireland. These people seem to be genetically very similar to modern Irish and brought a unique culture defined by beaker-shaped vessels.
    We also discussed controversies such as the timing of the arrival of the Irish language, and the patterns of interaction across the Atlantic facade, of which Ireland was part (which resulted in features such as the spread of Megalith culture to Ireland from the mainland.”
    Last edited by Heber; 03-14-2019 at 09:14 PM.
    Gerard Corcoran
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  3. #2432
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    Ancient DNA is a powerful tool for studying the past – when archaeologists and geneticists work together

    DNA has moved beyond esoteric science and into the center of everyday conversations about identity, culture and politics. It’s also reshaping stories about the past as advances allow scientists to extract ancient DNA (aDNA) from skeletons found at archaeological sites.

    With each ancient genetic sequence, scientists learn new information about how people moved around and interacted in the ancient world. In some cases, this has helped overturn theories and resolve age-old debates.

    But the aDNA “revolution” has also caused friction among geneticists, archaeologists and others over how this research is done. As archaeologists who collaborate on aDNA projects, we’ve witnessed these tensions firsthand. What lies at the heart of this rift, and how can these disciplines work together to better research humanity’s past?

    .....
    Communication and cooperation go a long way, but fixing the system ultimately requires a shift in how science is funded and rewarded. And the public has a key role to play as the taxpayers who fund scientific research and consume its findings. A scientifically literate society can demand work that meets ethical guidelines and provides meaningful insights about our past. Together, scientists and the public can set the tone for what aDNA research becomes and how we use it to explore our shared human heritage.

    https://theconversation.com/ancient-...ource=facebook
    Last edited by Heber; 03-14-2019 at 10:32 PM.
    Gerard Corcoran
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  5. #2433
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    We performed Y-chromosome haplogroup determination (Table S4) using the nomenclature of the International Society of Genetic Genealogy (http://www.isogg.org) version 11.110 (21 April 2016). We restricted to sequences with mapping quality ≥ 30 and bases with quality ≥ 30.
    We comment here on the striking Y-chromosome patterns observed during the Copper Age-Bronze Age transition in Iberia. All the Bronze Age males from Iberia with sufficient coverage (n=30) belonged to R1b-M269 (R1b1a1a2). Furthermore, all the R1b-M269 males with sufficient coverage (n=15) could be further classified as R1b-P312 (R1b1a1a2a1a2). Only one Bronze Age male, esp005.SG (7), had DNA sequences overlapping R1b-DF27 (R1b1a1a2a1a2a) and he was positive for the mutation. Two Bronze Age males, I6470 and I3997, had DNA sequences overlapping R1b-Z195 (R1b1a1a2a1a2a1), with I6470 being negative and I3997 positive. Eleven Bronze Age males had DNA sequences overlapping R1b-Z225 (R1b1a1a2a1a2a5), with only VAD001 being positive for the mutation (one Iron Age male, I3320, is also positive for this mutation). We thus detect three Bronze Age males who belonged to DF27 (154, 155), confirming its presence in Bronze Age Iberia. The other Iberian Bronze Age males could belong to DF27 as well, but the extremely low recovery rate of this SNP in our dataset prevented us to study its true distribution. All the Iberian Bronze Age males with overlapping sequences at R1b-L21 were negative for this mutation. Therefore, we can rule out Britain as a plausible proximate origin since contemporaneous British males are derived for the L21 subtype.

    https://reich.hms.harvard.edu/sites/...Supplement.pdf

    http://science.sciencemag.org/conten...blesS1-S5.xlsx
    Last edited by Heber; 03-14-2019 at 11:10 PM.
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    Quote Originally Posted by Heber View Post
    Eleven Bronze Age males had DNA sequences overlapping R1b-Z225 (R1b1a1a2a1a2a5), with only VAD001 being positive for the mutation (one Iron Age male, I3320, is also positive for this mutation).https://reich.hms.harvard.edu/sites/...Supplement.pdf

    http://science.sciencemag.org/conten...blesS1-S5.xlsx
    Very interesting. My maternal grandfather, whose paternal line comes from Portugal, belonged to a clade of R1b-Z225!

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    Published on Mar 14, 2019
    In this article, Villalba-Mouco et al. report new genomic data from the Iberian Peninsula. Iberian hunter-gatherers show dual Late Pleistocene genetic ancestry as a result of the admixture from different refugia. This mixed Late Pleistocene ancestry can be traced in the Iberian Neolithic farmers.

    http://www.cell.com/current-biology/f....

    V. Villalba-Mouco, M.S. van de Loosdrecht, C. Posth, R. Mora, J. Martínez-Moreno, M. Rojo-Guerra, Domingo C. Salazar-García, J.I. Royo-Guillén, Michael Kunst, H. Rougier, et al. (2019). Survival of Late Pleistocene Hunter-Gatherer Ancestry in the Iberian Peninsula. Curr. Biol. 29.

    http://www.cell.com/current-biology/home.

    https://www.youtube.com/watch?v=-2FyTBId76k
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    Doctors Julian Reed and Barbara Sullivan, fall in love with each other and with the idea of cloning a Neanderthal from ancient DNA. Against the express directive of University administrators they follow through on this audacious idea. The result is William: the first Neanderthal to walk the earth for some 35,000 years. William tries his best to fit into the world around him. But his distinctive physical features and his unique way of thinking--his "otherness"--set him apart. William's story is powerful and unique, but his struggle to find love and assert his own identity in a hostile world is universal -- and timeless. William is directed by producer / filmmaker Tim Disney, of the films A Question of Faith, Tempesta, and American Violet previously. The screenplay is written by J.T. Allen and Tim Disney. Dada Films will release Disney's William in select theaters starting April 12th this spring. For more, visit the film's official website.

    https://www.youtube.com/watch?v=PApVVu4Mj7U
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    Quote Originally Posted by Heber View Post
    Doctors Julian Reed and Barbara Sullivan, fall in love with each other and with the idea of cloning a Neanderthal from ancient DNA. Against the express directive of University administrators they follow through on this audacious idea. The result is William: the first Neanderthal to walk the earth for some 35,000 years. William tries his best to fit into the world around him. But his distinctive physical features and his unique way of thinking--his "otherness"--set him apart. William's story is powerful and unique, but his struggle to find love and assert his own identity in a hostile world is universal -- and timeless. William is directed by producer / filmmaker Tim Disney, of the films A Question of Faith, Tempesta, and American Violet previously. The screenplay is written by J.T. Allen and Tim Disney. Dada Films will release Disney's William in select theaters starting April 12th this spring. For more, visit the film's official website.

    https://www.youtube.com/watch?v=PApVVu4Mj7U
    From an original idea by Mary Shelley.

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