Italy is an important place. It is a crossroads in the Mediterranean. It's also right in the middle of the Cardial Wares Neolithic Advance, as a staging point.
However, Italy is huge north to south. I think it is important to dissect it as it has different prehistories and geographies.
One area that has to be treated uniquely for sure is North Italy, but to emphasize the point, I like to call it what the Romans called it, Cisalpine Gaul - "Gaul this side of the Alps." Wikipedia says, "Cisalpine Gaul, also called Gallia Citerior or Gallia Togata, was a Roman province until 41 BC, when it was merged into Roman Italy. It was that part of Gallia, the land of the Gauls, which lay south and east of the Alps, as opposed to Gallia Transalpina. Its inhabitants were primarily Celtic since the expulsion of the Etruscans.
The province was bounded on the north and west by the Alps, in the south as far as Placentia by the river Po, and then by the Apennines and the river Rubicon, and in the east by the Adriatic Sea"
http://en.wikipedia.org/wiki/Cisalpine_Gaul
I suspect that Italians would also consider Peninsular Italy to be somewhat zonal as well. I would have to think Puglia, Calabria, Sicily and Sardinia have some uniquenesses from the central part of the peninsula. Of course, there must be quite a difference between Genoa and Trieste too. I've got family and friends from Trieste. I think there is some Slavic genetic influence in that region.
I suppose, since the Neolithic advances are so significant, we should start with a picture of the Cardial Wares advance.
http://en.wikipedia.org/wiki/File:Cardial_map.png
"The earliest date in Italy comes from Coppa Nevigata on the Adriatic coast of southern Italy, perhaps as early as 6000 cal B.C. Also during Su Carroppu civilization in Sardinia, already in its early stages (low strata into Su Coloru cave, c. 6000 BC) early examples of cardial pottery appear."
I've seen estimates for M269 of anywhere from 4000 to 8000 years old (Mike Hammer, FTDNA conference). I think Vince Vizachero use to use this as well informally.
I've chided folks on this, but I can see why one would make sure to use the 8000 (6000 BC) as an upper range just to make sure that leaves room for the Cardial Wares in Italy. Marko Helinila calculates the age of M269 as 5700 years ago (3700 BC) and Anatole Kylosov calculates 7000 years ago (5000 BC), but probably the upper range of 6000 BC is quite fair.
What's the story of the ancient Latin League? Where are the Latin tribes thought to have come from prior to Latium?
http://en.wikipedia.org/wiki/Ancient_peoples_of_Italy
Can we connect them back to Remedello? or ?
What about the Etruscans? Wikipedia says "J. P. Mallory compares the Etruscans to other remnant non Indo-European central Mediterranean populations, such as the Basques of the Iberian Peninsula and southern France, who absorbed the art styles and alphabet of their Greek neighbors."
Is there good reason to think the Etruscans come from Anatolia or is that disproven?